Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage

BACKGROUND: The MYC protein controls cellular functions such as differentiation, proliferation, and apoptosis. In response to genotoxic agents, cells overexpressing MYC undergo apoptosis. However, the MYC-regulated effectors acting upstream of the mitochondrial apoptotic pathway are still unknown. P...

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Detalles Bibliográficos
Autores principales: Guerra, Lina, Albihn, Ami, Tronnersjö, Susanna, Yan, Qinzi, Guidi, Riccardo, Stenerlöw, Bo, Sterzenbach, Torsten, Josenhans, Christine, Fox, James G., Schauer, David B., Thelestam, Monica, Larsson, Lars-Gunnar, Henriksson, Marie, Frisan, Teresa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811743/
https://www.ncbi.nlm.nih.gov/pubmed/20111719
http://dx.doi.org/10.1371/journal.pone.0008924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811743/
https://www.ncbi.nlm.nih.gov/pubmed/20111719
http://dx.doi.org/10.1371/journal.pone.0008924

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