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Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model
INTRODUCTION: Recombinant human soluble thrombomodulin (rhsTM) is newly developed for the treatment of DIC. The purpose of this study was to evaluate the efficacy of the concomitant administration of rhsTM and antithrombin (AT). METHODS: In the first series, rats were treated with either 62.5, 125,...
Autores principales: | Iba, Toshiaki, Nakarai, Etsuro, Takayama, Toshio, Nakajima, Kenji, Sasaoka, Tetsumasa, Ohno, Yoichi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811901/ https://www.ncbi.nlm.nih.gov/pubmed/20003418 http://dx.doi.org/10.1186/cc8210 |
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