Cargando…

Defective Secretion of Islet Hormones in Chromogranin-B Deficient Mice

Granins are major constituents of dense-core secretory granules in neuroendocrine cells, but their function is still a matter of debate. Work in cell lines has suggested that the most abundant and ubiquitously expressed granins, chromogranin A and B (CgA and CgB), are involved in granulogenesis and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Obermüller, Stefanie, Calegari, Federico, King, Angus, Lindqvist, Anders, Lundquist, Ingmar, Salehi, Albert, Francolini, Maura, Rosa, Patrizia, Rorsman, Patrik, Huttner, Wieland B., Barg, Sebastian
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812483/ https://www.ncbi.nlm.nih.gov/pubmed/20126668 http://dx.doi.org/10.1371/journal.pone.0008936

Ejemplares similares

Insulin Secretion: A High-affinity Ca(2+) Sensor After All?
por: Barg, Sebastian, et al.
Publicado: (2004)

A Variation on the Theme: SGLT2 Inhibition and Glucagon Secretion in Human Islets
por: Hodson, David J., et al.
Publicado: (2020)

Metformin Ameliorates Dysfunctional Traits of Glibenclamide- and Glucose-Induced Insulin Secretion by Suppression of Imposed Overactivity of the Islet Nitric Oxide Synthase-NO System
por: Lundquist, Ingmar, et al.
Publicado: (2016)

Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
por: Salehi, Albert, et al.
Publicado: (2008)

Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
por: Salehi, Albert, et al.
Publicado: (2008)

Correction: Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
por: Salehi, Albert, et al.
Publicado: (2008)

Correction: Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
por: Salehi, Albert, et al.
Publicado: (2008)

SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells
por: Eliasson, Lena, et al.
Publicado: (2003)

Glucagon secretion from pancreatic α-cells
por: Briant, Linford, et al.
Publicado: (2016)

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets
por: Briant, Linford J.B., et al.
Publicado: (2018)

Essential Role of the Disulfide-bonded Loop of Chromogranin B for Sorting to Secretory Granules Is Revealed by Expression of a Deletion Mutant in the Absence of Endogenous Granin Synthesis
por: Krömer, Andreas, et al.
Publicado: (1998)

Adrenaline Stimulates Glucagon Secretion in Pancreatic A-Cells by Increasing the Ca(2+) Current and the Number of Granules Close to the L-Type Ca(2+) Channels
por: Gromada, Jesper, et al.
Publicado: (1997)

Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets
por: Ramracheya, Reshma, et al.
Publicado: (2010)

Response to Comment on Satin et al. “Take Me To Your Leader”: An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets. Diabetes 2020;69:830–836
por: Satin, Leslie S., et al.
Publicado: (2020)

Oscillations, Intercellular Coupling, and Insulin Secretion in Pancreatic β Cells
por: MacDonald, Patrick E, et al.
Publicado: (2006)

Low Efficacy of Chromogranin A Elimination by Therapeutic Plasma Exchange for Treatment of Chromogranin A Tubulopathy
por: Hakroush, Samy, et al.
Publicado: (2021)

Functional identification of islet cell types by electrophysiological fingerprinting
por: Briant, Linford J. B., et al.
Publicado: (2017)

Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon
por: Collins, S. C., et al.
Publicado: (2008)

Chromogranin A: An Endocrine Factor of Pregnancy
por: Bralewska, Michalina, et al.
Publicado: (2023)

Chromogranin-A production and fragmentation in patients with Takayasu arteritis
por: Tombetti, Enrico, et al.
Publicado: (2016)

‘Resistance is futile?’ – paradoxical inhibitory effects of K(ATP) channel closure in glucagon‐secreting α‐cells
por: Zhang, Quan, et al.
Publicado: (2020)

Chromogranin/secretogranin proteins in murine heart: myocardial production of chromogranin A fragment catestatin (Chga(364–384))
por: Biswas, Nilima, et al.
Publicado: (2010)

Chromogranin A plasma levels predict mortality in COVID-19
por: De Lorenzo, Rebecca, et al.
Publicado: (2022)

Live Imaging at the Onset of Cortical Neurogenesis Reveals Differential Appearance of the Neuronal Phenotype in Apical versus Basal Progenitor Progeny
por: Attardo, Alessio, et al.
Publicado: (2008)

α-cell glucokinase suppresses glucose-regulated glucagon secretion
por: Basco, Davide, et al.
Publicado: (2018)

A K(ATP) Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans
por: MacDonald, Patrick E, et al.
Publicado: (2007)

The surging role of Chromogranin A in cardiovascular homeostasis
por: Tota, Bruno, et al.
Publicado: (2014)

Chromogranin A in the Laboratory Diagnosis of Pheochromocytoma and Paraganglioma
por: Bílek, Radovan, et al.
Publicado: (2019)

Chromogranin A regulates neuroblastoma proliferation and phenotype
por: Zhang, Dongyun, et al.
Publicado: (2019)

The mechanisms of chromogranin B-regulated Cl(−) homeostasis
por: Jiang, Qiu-Xing, et al.
Publicado: (2022)

IGF-1 drives chromogranin A secretion via activation of Arf1 in human neuroendocrine tumour cells
por: Münzberg, Christin, et al.
Publicado: (2015)

Chromogranin B (CHGB) is dimorphic and responsible for dominant anion channels delivered to cell surface via regulated secretion
por: Yadav, Gaya P., et al.
Publicado: (2023)

Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
por: Golec, Ewelina, et al.
Publicado: (2022)

TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet β-Cells
por: da Silva Xavier, Gabriela, et al.
Publicado: (2009)

Characterisation of circulating chromogranin A in human cancer patients.
por: Corti, A., et al.
Publicado: (1996)

Chromogranin A expression in plasma of critically ill patients
por: Lavaux, T, et al.
Publicado: (2010)

Regulatory Peptides from Chromogranin A and Secretogranin II
por: Helle, Karen B.
Publicado: (2010)

Chromogranins can be measured in samples from cats and dogs
por: Stridsberg, Mats, et al.
Publicado: (2014)

Elevated serum levels of Chromogranin A in hepatocellular carcinoma
por: Biondi, Antonio, et al.
Publicado: (2012)

Altered Chromogranin A Circulating Levels in Meniere's Disease
por: Teggi, Roberto, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_r3v7fe2fo4agt8ou3jfj73jd4h