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Nuclear Expression of KLF6 Tumor Suppressor Factor Is Highly Associated with Overexpression of ERBB2 Oncoprotein in Ductal Breast Carcinomas

BACKGROUND: Krüppel-like factor 6 (KLF6) is an evolutionarily conserved and ubiquitously expressed protein that belongs to the mammalian Sp1/KLF family of transcriptional regulators. Though KLF6 is a transcription factor and harbors a nuclear localization signal it is not systematically located in t...

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Detalles Bibliográficos
Autores principales: Gehrau, Ricardo C., D'Astolfo, Diego S., Dumur, Catherine I., Bocco, José L., Koritschoner, Nicolás P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812494/
https://www.ncbi.nlm.nih.gov/pubmed/20126619
http://dx.doi.org/10.1371/journal.pone.0008929