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Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels
In the metazoan replication timing program, clusters of replication origins located in different subchromosomal domains fire at different times during S phase. We have used Xenopus laevis egg extracts to drive an accelerated replication timing program in mammalian nuclei. Although replicative stress...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812520/ https://www.ncbi.nlm.nih.gov/pubmed/20083602 http://dx.doi.org/10.1083/jcb.200911037 |