CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription

Retroviruses pack multiple genes into relatively small genomes by encoding several genes in the same genomic region with overlapping reading frames. Both sense and antisense HIV-1 transcripts contain open reading frames for known functional proteins as well as numerous alternative reading frames (AR...

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Detalles Bibliográficos
Autores principales: Bansal, Anju, Carlson, Jonathan, Yan, Jiyu, Akinsiku, Olusimidele T., Schaefer, Malinda, Sabbaj, Steffanie, Bet, Anne, Levy, David N., Heath, Sonya, Tang, Jianming, Kaslow, Richard A., Walker, Bruce D., Ndung’u, Thumbi, Goulder, Philip J., Heckerman, David, Hunter, Eric, Goepfert, Paul A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812545/
https://www.ncbi.nlm.nih.gov/pubmed/20065064
http://dx.doi.org/10.1084/jem.20092060

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