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The nonpolymorphic MHC Qa-1(b) mediates CD8(+) T cell surveillance of antigen-processing defects
The nonclassical major histocompatibility complex (MHC) Qa-1(b) accommodates monomorphic leader peptides and functions as a ligand for germ line receptors CD94/NKG2, which are expressed by natural killer cells and CD8(+) T cells. We here describe that the conserved peptides are replaced by a novel p...
Autores principales: | Oliveira, Cláudia C., van Veelen, Peter A., Querido, Bianca, de Ru, Arnoud, Sluijter, Marjolein, Laban, Sandra, Drijfhout, Jan W., van der Burg, Sjoerd H., Offringa, Rienk, van Hall, Thorbald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812552/ https://www.ncbi.nlm.nih.gov/pubmed/20038604 http://dx.doi.org/10.1084/jem.20091429 |
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