The nonpolymorphic MHC Qa-1(b) mediates CD8(+) T cell surveillance of antigen-processing defects

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The nonclassical major histocompatibility complex (MHC) Qa-1(b) accommodates monomorphic leader peptides and functions as a ligand for germ line receptors CD94/NKG2, which are expressed by natural killer cells and CD8(+) T cells. We here describe that the conserved peptides are replaced by a novel p...

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Detalles Bibliográficos
Autores principales: Oliveira, Cláudia C., van Veelen, Peter A., Querido, Bianca, de Ru, Arnoud, Sluijter, Marjolein, Laban, Sandra, Drijfhout, Jan W., van der Burg, Sjoerd H., Offringa, Rienk, van Hall, Thorbald
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812552/
https://www.ncbi.nlm.nih.gov/pubmed/20038604
http://dx.doi.org/10.1084/jem.20091429
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