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Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse

Nuclear receptor coactivator [peroxisome proliferator-activated receptor-binding protein (PBP)/mediator subunit 1 (MED1)] is a critical component of the mediator transcription complex. Disruption of this gene in the mouse results in embryonic lethality. Using the PBP/MED1 liver conditional null (PBP...

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Detalles Bibliográficos
Autores principales:	Matsumoto, Kojiro, Huang, Jiansheng, Viswakarma, Navin, Bai, Liang, Jia, Yuzhi, Zhu, Yiwei Tony, Yang, Gongshe, Borensztajn, Jayme, Rao, M.Sambasiva, Zhu, Yi-Jun, Reddy, Janardan K.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Carcinogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812575/ https://www.ncbi.nlm.nih.gov/pubmed/20007298 http://dx.doi.org/10.1093/carcin/bgp306

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