Hydrodynamic properties of cyclodextrin molecules in dilute solutions

Three well-known representatives of the cyclodextrin family were completely characterized by molecular hydrodynamics methods in three different solvents. For the first time the possibility of an estimation of velocity sedimentation coefficients s between 0.15 and 0.5 S by the numerical solution of t...

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Detalles Bibliográficos
Autores principales: Pavlov, Georges M., Korneeva, Evguenia V., Smolina, Natalia A., Schubert, Ulrich S.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812710/
https://www.ncbi.nlm.nih.gov/pubmed/19159925
http://dx.doi.org/10.1007/s00249-008-0394-9
Descripción
Sumario:Three well-known representatives of the cyclodextrin family were completely characterized by molecular hydrodynamics methods in three different solvents. For the first time the possibility of an estimation of velocity sedimentation coefficients s between 0.15 and 0.5 S by the numerical solution of the Lamm equation is shown. Comparison of the experimental hydrodynamic characteristics of the cyclodextrins with theoretical calculations for toroidal molecules allows an estimation of the thickness of the solvent layers on the surface of cyclodextrin molecules.

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