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A blind deconvolution approach to high-resolution mapping of transcription factor binding sites from ChIP-seq data

We present CSDeconv, a computational method that determines locations of transcription factor binding from ChIP-seq data. CSDeconv differs from prior methods in that it uses a blind deconvolution approach that allows closely-spaced binding sites to be called accurately. We apply CSDeconv to novel Ch...

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Detalles Bibliográficos
Autores principales: Lun, Desmond S, Sherrid, Ashley, Weiner, Brian, Sherman, David R, Galagan, James E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812949/
https://www.ncbi.nlm.nih.gov/pubmed/20028542
http://dx.doi.org/10.1186/gb-2009-10-12-r142