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Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus

The objective of this work was to determine the linear and non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus and to study the changes in mechanical properties throughout the thickness of the thrombus. Samples are gathered from thrombi of seven patients. Linear viscoelastic data...

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Autores principales: van Dam, Evelyne A., Dams, Susanne D., Peters, Gerrit W. M., Rutten, Marcel C. M., Schurink, Geert Willem H., Buth, Jaap, van de Vosse, Frans N.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813187/
https://www.ncbi.nlm.nih.gov/pubmed/17492322
http://dx.doi.org/10.1007/s10237-007-0080-3
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author van Dam, Evelyne A.
Dams, Susanne D.
Peters, Gerrit W. M.
Rutten, Marcel C. M.
Schurink, Geert Willem H.
Buth, Jaap
van de Vosse, Frans N.
author_facet van Dam, Evelyne A.
Dams, Susanne D.
Peters, Gerrit W. M.
Rutten, Marcel C. M.
Schurink, Geert Willem H.
Buth, Jaap
van de Vosse, Frans N.
author_sort van Dam, Evelyne A.
collection PubMed
description The objective of this work was to determine the linear and non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus and to study the changes in mechanical properties throughout the thickness of the thrombus. Samples are gathered from thrombi of seven patients. Linear viscoelastic data from oscillatory shear experiments show that the change of properties throughout the thrombus is different for each thrombus. Furthermore the variations found within one thrombus are of the same order of magnitude as the variation between patients. To study the non-linear regime, stress relaxation experiments are performed. To describe the phenomena observed experimentally, a non-linear multimode model is presented. The parameters for this model are obtained by fitting this model successfully to the experiments. The model cannot only describe the average stress response for all thrombus samples but also the highest and lowest stress responses. To determine the influence on the wall stress of the behavior observed the model proposed needs to implemented in the finite element wall stress analysis.
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spelling pubmed-28131872010-01-29 Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus van Dam, Evelyne A. Dams, Susanne D. Peters, Gerrit W. M. Rutten, Marcel C. M. Schurink, Geert Willem H. Buth, Jaap van de Vosse, Frans N. Biomech Model Mechanobiol Original Paper The objective of this work was to determine the linear and non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus and to study the changes in mechanical properties throughout the thickness of the thrombus. Samples are gathered from thrombi of seven patients. Linear viscoelastic data from oscillatory shear experiments show that the change of properties throughout the thrombus is different for each thrombus. Furthermore the variations found within one thrombus are of the same order of magnitude as the variation between patients. To study the non-linear regime, stress relaxation experiments are performed. To describe the phenomena observed experimentally, a non-linear multimode model is presented. The parameters for this model are obtained by fitting this model successfully to the experiments. The model cannot only describe the average stress response for all thrombus samples but also the highest and lowest stress responses. To determine the influence on the wall stress of the behavior observed the model proposed needs to implemented in the finite element wall stress analysis. Springer-Verlag 2007-05-10 2008-04 /pmc/articles/PMC2813187/ /pubmed/17492322 http://dx.doi.org/10.1007/s10237-007-0080-3 Text en © Springer-Verlag 2007
spellingShingle Original Paper
van Dam, Evelyne A.
Dams, Susanne D.
Peters, Gerrit W. M.
Rutten, Marcel C. M.
Schurink, Geert Willem H.
Buth, Jaap
van de Vosse, Frans N.
Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus
title Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus
title_full Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus
title_fullStr Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus
title_full_unstemmed Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus
title_short Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus
title_sort non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813187/
https://www.ncbi.nlm.nih.gov/pubmed/17492322
http://dx.doi.org/10.1007/s10237-007-0080-3
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