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Recombination Rate and Selection Strength in HIV Intra-patient Evolution
The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment. To understand and model the evolution of HIV quantitatively, the parameters governing genetic diversification and the strength of se...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813257/ https://www.ncbi.nlm.nih.gov/pubmed/20126527 http://dx.doi.org/10.1371/journal.pcbi.1000660 |