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CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells

While CD8+ T cells are clearly important in controlling virus replication during HIV and SIV infections, the mechanisms underlying this antiviral effect remain poorly understood. In this study, we assessed the in vivo effect of CD8+ lymphocyte depletion on the lifespan of productively infected cells...

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Detalles Bibliográficos
Autores principales:	Klatt, Nichole R., Shudo, Emi, Ortiz, Alex M., Engram, Jessica C., Paiardini, Mirko, Lawson, Benton, Miller, Michael D., Else, James, Pandrea, Ivona, Estes, Jacob D., Apetrei, Cristian, Schmitz, Joern E., Ribeiro, Ruy M., Perelson, Alan S., Silvestri, Guido
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813271/ https://www.ncbi.nlm.nih.gov/pubmed/20126441 http://dx.doi.org/10.1371/journal.ppat.1000747

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