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PTEN status in advanced colorectal cancer treated with cetuximab

BACKGROUND: Loss of phosphatase and tensin homologue deleted in chromosome 10 (PTEN) function in advanced colorectal cancer (CRC) may represent one of the resistance mechanisms to cetuximab by interfering with the epidermal growth factor receptor signal transduction pathway. METHODS: PTEN expression...

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Detalles Bibliográficos
Autores principales:	Negri, F V, Bozzetti, C, Lagrasta, C A, Crafa, P, Bonasoni, M P, Camisa, R, Pedrazzi, G, Ardizzoni, A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813733/ https://www.ncbi.nlm.nih.gov/pubmed/19953097 http://dx.doi.org/10.1038/sj.bjc.6605471

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