Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival

BACKGROUND: Collagen and calcium-binding EGF domains 1 (CCBE1) is an uncharacterised gene that has down-regulated expression in breast cancer. As CCBE1 maps to 18q21.32, a region frequently exhibiting loss of heterozygosity in ovarian cancer, the aim of this study was to determine the expression and...

Descripción completa

Detalles Bibliográficos
Autores principales: Barton, C A, Gloss, B S, Qu, W, Statham, A L, Hacker, N F, Sutherland, R L, Clark, S J, O'Brien, P M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813742/
https://www.ncbi.nlm.nih.gov/pubmed/19935792
http://dx.doi.org/10.1038/sj.bjc.6605429

Ejemplares similares

Ejemplares similares