The Translation Regulatory Subunit eIF3f Controls the Kinase-Dependent mTOR Signaling Required for Muscle Differentiation and Hypertrophy in Mouse

The mTORC1 pathway is required for both the terminal muscle differentiation and hypertrophy by controlling the mammalian translational machinery via phosphorylation of S6K1 and 4E-BP1. mTOR and S6K1 are connected by interacting with the eIF3 initiation complex. The regulatory subunit eIF3f plays a m...

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Detalles Bibliográficos
Autores principales: Csibi, Alfredo, Cornille, Karen, Leibovitch, Marie-Pierre, Poupon, Anne, Tintignac, Lionel A., Sanchez, Anthony M. J., Leibovitch, Serge A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813880/
https://www.ncbi.nlm.nih.gov/pubmed/20126553
http://dx.doi.org/10.1371/journal.pone.0008994

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