A replication-incompetent Rift Valley fever vaccine: Chimeric virus-like particles protect mice and rats against lethal challenge

Virus-like particles (VLPs) present viral antigens in a native conformation and are effectively recognized by the immune system and therefore are considered as suitable and safe vaccine candidates against many viral diseases. Here we demonstrate that chimeric VLPs containing Rift Valley fever virus...

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Detalles Bibliográficos
Autores principales: Mandell, Robert B., Koukuntla, Ramesh, Mogler, Laura J.K., Carzoli, Andrea K., Freiberg, Alexander N., Holbrook, Michael R., Martin, Brian K., Staplin, William R., Vahanian, Nicholas N., Link, Charles J., Flick, Ramon
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813982/
https://www.ncbi.nlm.nih.gov/pubmed/19932911
http://dx.doi.org/10.1016/j.virol.2009.11.001

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