Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival

Recent evidence suggests the Akt-mTOR pathway may play a role in development of low-grade gliomas (LGG). We sought to evaluate whether activation of this pathway correlates with survival in LGG by examining expression patterns of proteins within this pathway. Forty-five LGG tumor specimens from newl...

Descripción completa

Detalles Bibliográficos
Autores principales: McBride, Sean M., Perez, Daniel A., Polley, Mei-Yin, Vandenberg, Scott R., Smith, Justin S., Zheng, Shichun, Lamborn, Kathleen R., Wiencke, John K., Chang, Susan M., Prados, Michael D., Berger, Mitchel S., Stokoe, David, Haas-Kogan, Daphne A.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Laboratory Investigation - Human/Animal Tissue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814032/
https://www.ncbi.nlm.nih.gov/pubmed/19705067
http://dx.doi.org/10.1007/s11060-009-0004-4

Ejemplares similares

Ejemplares similares