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The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans

The Penicillium chrysogenum antifungal protein PAF inhibits polar growth and induces apoptosis in Aspergillus nidulans. We report here that two signalling cascades are implicated in its antifungal activity. PAF activates the cAMP/protein kinase A (Pka) signalling cascade. A pkaA deletion mutant exhi...

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Detalles Bibliográficos
Autores principales: Binder, Ulrike, Oberparleiter, Christoph, Meyer, Vera, Marx, Florentine
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814085/
https://www.ncbi.nlm.nih.gov/pubmed/19889092
http://dx.doi.org/10.1111/j.1365-2958.2009.06936.x