Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer

The EphA2 receptor tyrosine kinase is overexpressed in a variety of human epithelial cancers and is a determinant of malignant cellular behavior in pancreatic adenocarcinoma cells. Moreover, it is expressed in tumor endothelium and its activation promotes angiogenesis. To better clarify the therapeu...

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Detalles Bibliográficos
Autores principales: Ansuini, Helenia, Meola, Annalisa, Gunes, Zeynep, Paradisi, Valentina, Pezzanera, Monica, Acali, Stefano, Santini, Claudia, Luzzago, Alessandra, Mori, Federica, Lazzaro, Domenico, Ciliberto, Gennaro, Nicosia, Alfredo, La Monica, Nicola, Vitelli, Alessandra
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814375/
https://www.ncbi.nlm.nih.gov/pubmed/20130824
http://dx.doi.org/10.1155/2009/951917

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