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OXavidin for Tissue Targeting Biotinylated Therapeutics

Avidin is a glycoprotein from hen egg white that binds biotin with very high affinity. Here we describe OXavidin, a product containing aldehyde groups, obtained by ligand-assisted sugar oxidation of avidin by sodium periodate. OXavidin chemically reacts with cellular and tissue proteins through Schi...

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Detalles Bibliográficos
Autores principales: De Santis, Rita, Albertoni, Claudio, Rosi, Antonio, Leoni, Barbara, Petronzelli, Fiorella, D'Alessio, Valeria, Nucera, Eleonora, Salvatori, Giovanni, Paganelli, Giovanni, Verdoliva, Antonio, Carminati, Paolo, Nuzzolo, Carlo Antonio
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814378/
https://www.ncbi.nlm.nih.gov/pubmed/20130784
http://dx.doi.org/10.1155/2009/921434