Regulatory T Cells and Human Myeloid Dendritic Cells Promote Tolerance via Programmed Death Ligand-1

Immunotherapy using regulatory T cells (Treg) has been proposed, yet cellular and molecular mechanisms of human Tregs remain incompletely characterized. Here, we demonstrate that human Tregs promote the generation of myeloid dendritic cells (DC) with reduced capacity to stimulate effector T cell res...

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Detalles Bibliográficos
Autores principales: Amarnath, Shoba, Costanzo, Carliann M., Mariotti, Jacopo, Ullman, Jessica L., Telford, William G., Kapoor, Veena, Riley, James L., Levine, Bruce L., June, Carl H., Fong, Timothy, Warner, Noel L., Fowler, Daniel H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814822/
https://www.ncbi.nlm.nih.gov/pubmed/20126379
http://dx.doi.org/10.1371/journal.pbio.1000302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814822/
https://www.ncbi.nlm.nih.gov/pubmed/20126379
http://dx.doi.org/10.1371/journal.pbio.1000302

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