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Expression of Cartilage Developmental Genes in Hoxc8- and Hoxd4-Transgenic Mice
Hox genes encode transcription factors, which regulate skeletal patterning and chondrocyte differentiation during the development of cartilage, the precursor to mature bone. Overexpression of the homeobox transcription factors Hoxc8 and Hoxd4 causes severe cartilage defects due to delay in cartilage...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814844/ https://www.ncbi.nlm.nih.gov/pubmed/20126390 http://dx.doi.org/10.1371/journal.pone.0008978 |