The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase

The RNA-binding protein tristetraprolin (TTP) regulates expression of many cancer-associated and proinflammatory factors through binding AU-rich elements (ARE) in the 3'-untranslated region (3'UTR) and facilitating rapid mRNA decay. Here we report on the ability of TTP to act in an anti-pr...

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Detalles Bibliográficos
Autores principales: Sanduja, Sandhya, Kaza, Vimala, Dixon, Dan A.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815738/
https://www.ncbi.nlm.nih.gov/pubmed/20157568

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