Increasing tPA Activity in Astrocytes Induced by Multipotent Mesenchymal Stromal Cells Facilitate Neurite Outgrowth after Stroke in the Mouse

We demonstrate that tissue plasminogen activator (tPA) and its inhibitors contribute to neurite outgrowth in the central nervous system (CNS) after treatment of stroke with multipotent mesenchymal stromal cells (MSCs). In vivo, administration of MSCs to mice subjected to middle cerebral artery occlu...

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Detalles Bibliográficos
Autores principales: Xin, Hongqi, Li, Yi, Shen, Li Hong, Liu, Xianshuang, Wang, Xinli, Zhang, Jing, Pourabdollah-Nejad D, Siamak, Zhang, Chunling, Zhang, Li, Jiang, Hao, Zhang, Zheng Gang, Chopp, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815778/
https://www.ncbi.nlm.nih.gov/pubmed/20140248
http://dx.doi.org/10.1371/journal.pone.0009027

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