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Melanoma Cells Treated with GGTI and IFN-γ Allow Murine Vaccination and Enhance Cytotoxic Response against Human Melanoma Cells

BACKGROUND: Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major histocompatibility antigens (MHC-I) and costimulatory molecules. We have previously shown that geranylgeranyl transferase inhibition (done with GGTI-298) stimulates anti-mel...

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Detalles Bibliográficos
Autores principales:	Sarrabayrouse, Guillaume, Pich, Christine, Moriez, Raphaël, Armand-Labit, Virginie, Rochaix, Philippe, Favre, Gilles, Tilkin-Mariamé, Anne-Françoise
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815789/ https://www.ncbi.nlm.nih.gov/pubmed/20140259 http://dx.doi.org/10.1371/journal.pone.0009043

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