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Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea

The aim of this study was to assess the implications of insulin resistance on the clinical and biochemical profiles of Korean type 2 diabetic patients. 122 patients with type 2 diabetes underwent a short insulin tolerance test to assess insulin resistance. Subjects were classified in tertiles accord...

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Detalles Bibliográficos
Autores principales: Park, Jong-Suk, Kim, Chul-Sik, Nam, Joo-Young, Kim, Dol-Mi, Jo, Min-Ho, Park, Jina, Ahn, Chul-Woo, Cha, Bong-Soo, Lim, Sung-Kil, Kim, Kyung-Rae, Lee, Hyun-Chul, Huh, Kap-Bum
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815832/
https://www.ncbi.nlm.nih.gov/pubmed/16127772
http://dx.doi.org/10.3349/ymj.2005.46.4.484
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author Park, Jong-Suk
Kim, Chul-Sik
Nam, Joo-Young
Kim, Dol-Mi
Jo, Min-Ho
Park, Jina
Ahn, Chul-Woo
Cha, Bong-Soo
Lim, Sung-Kil
Kim, Kyung-Rae
Lee, Hyun-Chul
Huh, Kap-Bum
author_facet Park, Jong-Suk
Kim, Chul-Sik
Nam, Joo-Young
Kim, Dol-Mi
Jo, Min-Ho
Park, Jina
Ahn, Chul-Woo
Cha, Bong-Soo
Lim, Sung-Kil
Kim, Kyung-Rae
Lee, Hyun-Chul
Huh, Kap-Bum
author_sort Park, Jong-Suk
collection PubMed
description The aim of this study was to assess the implications of insulin resistance on the clinical and biochemical profiles of Korean type 2 diabetic patients. 122 patients with type 2 diabetes underwent a short insulin tolerance test to assess insulin resistance. Subjects were classified in tertiles according to ISI (insulin sensitivity index), and the tertile I (the insulin-resistant group) and tertile III (the insulin-sensitive group) clinical and biochemical parameters were compared. Age, waist circumference (WC), systolic blood pressure (SBP), HbA1c, body fat content, and fasting plasma glucose were significantly higher in tertile I than tertile III (all p < 0.05). The frequency of hypertension and family history of cerebrovascular disease (CVD) were greater in tertile I than III (p < 0.05). To evaluate the factors affecting ISI, multiple regression was performed, and age, WC, SBP, HbA1c, and body fat content were found to be independently related to insulin resistance (p < 0.05). Old age, hypertension, central obesity, and poor glycemic control were identified as clinical parameters of insulin resistance in Korean type 2 diabetic patients.
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spelling pubmed-28158322010-02-04 Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea Park, Jong-Suk Kim, Chul-Sik Nam, Joo-Young Kim, Dol-Mi Jo, Min-Ho Park, Jina Ahn, Chul-Woo Cha, Bong-Soo Lim, Sung-Kil Kim, Kyung-Rae Lee, Hyun-Chul Huh, Kap-Bum Yonsei Med J Original Article The aim of this study was to assess the implications of insulin resistance on the clinical and biochemical profiles of Korean type 2 diabetic patients. 122 patients with type 2 diabetes underwent a short insulin tolerance test to assess insulin resistance. Subjects were classified in tertiles according to ISI (insulin sensitivity index), and the tertile I (the insulin-resistant group) and tertile III (the insulin-sensitive group) clinical and biochemical parameters were compared. Age, waist circumference (WC), systolic blood pressure (SBP), HbA1c, body fat content, and fasting plasma glucose were significantly higher in tertile I than tertile III (all p < 0.05). The frequency of hypertension and family history of cerebrovascular disease (CVD) were greater in tertile I than III (p < 0.05). To evaluate the factors affecting ISI, multiple regression was performed, and age, WC, SBP, HbA1c, and body fat content were found to be independently related to insulin resistance (p < 0.05). Old age, hypertension, central obesity, and poor glycemic control were identified as clinical parameters of insulin resistance in Korean type 2 diabetic patients. Yonsei University College of Medicine 2005-08-31 2005-08-31 /pmc/articles/PMC2815832/ /pubmed/16127772 http://dx.doi.org/10.3349/ymj.2005.46.4.484 Text en Copyright © 2005 The Yonsei University College of Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Park, Jong-Suk
Kim, Chul-Sik
Nam, Joo-Young
Kim, Dol-Mi
Jo, Min-Ho
Park, Jina
Ahn, Chul-Woo
Cha, Bong-Soo
Lim, Sung-Kil
Kim, Kyung-Rae
Lee, Hyun-Chul
Huh, Kap-Bum
Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea
title Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea
title_full Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea
title_fullStr Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea
title_full_unstemmed Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea
title_short Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea
title_sort characteristics of type 2 diabetes in terms of insulin resistance in korea
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815832/
https://www.ncbi.nlm.nih.gov/pubmed/16127772
http://dx.doi.org/10.3349/ymj.2005.46.4.484
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