Lack of nAChR Activity Depresses Cochlear Maturation and Up-Regulates GABA System Components: Temporal Profiling of Gene Expression in α9 Null Mice

BACKGROUND: It has previously been shown that deletion of chrna9, the gene encoding the α9 nicotinic acetylcholine receptor (nAChR) subunit, results in abnormal synaptic terminal structure. Additionally, all nAChR-mediated cochlear activity is lost, as characterized by a failure of the descending ef...

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Detalles Bibliográficos
Autores principales: Turcan, Sevin, Slonim, Donna K., Vetter, Douglas E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816210/
https://www.ncbi.nlm.nih.gov/pubmed/20140217
http://dx.doi.org/10.1371/journal.pone.0009058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816210/
https://www.ncbi.nlm.nih.gov/pubmed/20140217
http://dx.doi.org/10.1371/journal.pone.0009058

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