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Ribosylation Rapidly Induces α-Synuclein to Form Highly Cytotoxic Molten Globules of Advanced Glycation End Products

BACKGROUND: Alpha synuclein (α-Syn) is the main component of Lewy bodies which are associated with several neurodegenerative diseases such as Parkinson's disease. While the glycation with D-glucose that results in α-Syn misfold and aggregation has been studied, the effects of glycation with D-r...

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Detalles Bibliográficos
Autores principales:	Chen, Lan, Wei, Yan, Wang, Xueqing, He, Rongqiao
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816216/ https://www.ncbi.nlm.nih.gov/pubmed/20140223 http://dx.doi.org/10.1371/journal.pone.0009052

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