Aldosterone Upregulates Connective Tissue Growth Factor Gene Expression via p38 MAPK Pathway and Mineralocorticoid Receptor in Ventricular Myocytes

The effect of aldosterone on connective tissue growth factor (CTGF) was examined in rat embryonic ventricular myocytes. Upon aldosterone treatment, CTGF expression was significantly increased in a dose and time-dependent manner. To explore the molecular mechanism for this upregulation, we examined t...

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Detalles Bibliográficos
Autores principales: Lee, Young-Sam, Kim, Jeong-A, Kim, Koung Li, Jang, Hyung-Suk, Kim, Jeong-Min, Lee, Jae-Young, Shin, In-Soon, Lee, Jung-Sun, Suh, Wonhee, Choi, Jin-Ho, Jeon, Eun-Seok, Byun, Jonghoe, Kim, Duk-Kyung
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2004
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816296/
https://www.ncbi.nlm.nih.gov/pubmed/15608389
http://dx.doi.org/10.3346/jkms.2004.19.6.805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816296/
https://www.ncbi.nlm.nih.gov/pubmed/15608389
http://dx.doi.org/10.3346/jkms.2004.19.6.805

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