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Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex

The fine-scale structure of the majority of copy number variation (CNV) regions remains unknown. The killer immunoglobulin receptor (KIR) gene complex exhibits significant CNV. The evolutionary plasticity of the KIRs and their broad biomedical relevance makes it important to understand how these imm...

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Detalles Bibliográficos
Autores principales: Traherne, James A., Martin, Maureen, Ward, Rosemary, Ohashi, Maki, Pellett, Fawnda, Gladman, Dafna, Middleton, Derek, Carrington, Mary, Trowsdale, John
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816608/
https://www.ncbi.nlm.nih.gov/pubmed/19959527
http://dx.doi.org/10.1093/hmg/ddp538

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