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Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex
The fine-scale structure of the majority of copy number variation (CNV) regions remains unknown. The killer immunoglobulin receptor (KIR) gene complex exhibits significant CNV. The evolutionary plasticity of the KIRs and their broad biomedical relevance makes it important to understand how these imm...
Autores principales: | Traherne, James A., Martin, Maureen, Ward, Rosemary, Ohashi, Maki, Pellett, Fawnda, Gladman, Dafna, Middleton, Derek, Carrington, Mary, Trowsdale, John |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816608/ https://www.ncbi.nlm.nih.gov/pubmed/19959527 http://dx.doi.org/10.1093/hmg/ddp538 |
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