Lack of association between oestrogen receptor polymorphisms and change in bone mineral density with tamoxifen therapy

BACKGROUND: Tamoxifen, a selective oestrogen receptor (ER) modulator, increases bone mineral density (BMD) in postmenopausal women and decreases BMD in premenopausal women. We hypothesised that inherited variants in candidate genes involved in oestrogen signalling and tamoxifen metabolism might be a...

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Detalles Bibliográficos
Autores principales: Henry, N L, Nguyen, A, Azzouz, F, Li, L, Robarge, J, Philips, S, Cao, D, Skaar, T C, Rae, J M, Storniolo, A M, Flockhart, D A, Hayes, D F, Stearns, V
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816645/
https://www.ncbi.nlm.nih.gov/pubmed/19953095
http://dx.doi.org/10.1038/sj.bjc.6605460

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