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Class III β-tubulin expression and in vitro resistance to microtubule targeting agents

BACKGROUND: Class III β-tubulin overexpression is a marker of resistance to microtubule disruptors in vitro, in vivo and in the clinic for many cancers, including breast cancer. The aims of this study were to develop a new model of class III β-tubulin expression, avoiding the toxicity associated wit...

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Detalles Bibliográficos
Autores principales: Stengel, C, Newman, S P, Leese, M P, Potter, B V L, Reed, M J, Purohit, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816659/
https://www.ncbi.nlm.nih.gov/pubmed/20029418
http://dx.doi.org/10.1038/sj.bjc.6605489

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