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Class III β-tubulin expression and in vitro resistance to microtubule targeting agents
BACKGROUND: Class III β-tubulin overexpression is a marker of resistance to microtubule disruptors in vitro, in vivo and in the clinic for many cancers, including breast cancer. The aims of this study were to develop a new model of class III β-tubulin expression, avoiding the toxicity associated wit...
Autores principales: | Stengel, C, Newman, S P, Leese, M P, Potter, B V L, Reed, M J, Purohit, A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816659/ https://www.ncbi.nlm.nih.gov/pubmed/20029418 http://dx.doi.org/10.1038/sj.bjc.6605489 |
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