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Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence
Candida albicans, the major fungal pathogen of humans, causes life-threatening infections in immunocompromised individuals. Due to limited available therapy options, this can frequently lead to therapy failure and emergence of drug resistance. To improve current treatment strategies, we have combine...
Autores principales: | Epp, Elias, Vanier, Ghyslaine, Harcus, Doreen, Lee, Anna Y., Jansen, Gregor, Hallett, Michael, Sheppard, Don C., Thomas, David Y., Munro, Carol A., Mullick, Alaka, Whiteway, Malcolm |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816695/ https://www.ncbi.nlm.nih.gov/pubmed/20140196 http://dx.doi.org/10.1371/journal.ppat.1000753 |
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