Cargando…

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

The innate immune response is essential for controlling West Nile virus (WNV) infection but how this response is propagated and regulates adaptive immunity in vivo are not defined. Herein, we show that IPS-1, the central adaptor protein to RIG-I-like receptor (RLR) signaling, is essential for trigge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suthar, Mehul S., Ma, Daphne Y., Thomas, Sunil, Lund, Jennifer M., Zhang, Nu, Daffis, Stephane, Rudensky, Alexander Y., Bevan, Michael J., Clark, Edward A., Kaja, Murali-Krishna, Diamond, Michael S., Gale, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816698/ https://www.ncbi.nlm.nih.gov/pubmed/20140199 http://dx.doi.org/10.1371/journal.ppat.1000757

Ejemplares similares

Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8(+) T Cell Immune Responses against West Nile Virus Infection
por: Brien, James D., et al.
Publicado: (2011)

Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7
por: Daffis, Stephane, et al.
Publicado: (2009)

Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms
por: Daffis, Stephane, et al.
Publicado: (2007)

Systems analysis of West Nile virus infection
por: Suthar, Mehul S, et al.
Publicado: (2014)

Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes
por: Graham, Jessica B., et al.
Publicado: (2015)

Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses
por: Roe, Kelsey, et al.
Publicado: (2019)

The Innate Immune Playbook for Restricting West Nile Virus Infection
por: Quicke, Kendra M., et al.
Publicado: (2013)

IL-1β Signaling Promotes CNS-Intrinsic Immune Control of West Nile Virus Infection
por: Ramos, Hilario J., et al.
Publicado: (2012)

A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes
por: Suthar, Mehul S., et al.
Publicado: (2013)

A Temporal Role Of Type I Interferon Signaling in CD8(+) T Cell Maturation during Acute West Nile Virus Infection
por: Pinto, Amelia K., et al.
Publicado: (2011)

Virus and Host Determinants of West Nile Virus Pathogenesis
por: Diamond, Michael S.
Publicado: (2009)

A Mouse Model of Chronic West Nile Virus Disease
por: Graham, Jessica B., et al.
Publicado: (2016)

Immune Responses to West Nile Virus Infection in the Central Nervous System
por: Cho, Hyelim, et al.
Publicado: (2012)

Splenic macrophages are required for protective innate immunity against West Nile virus
por: Bryan, Marianne A., et al.
Publicado: (2018)

Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization
por: Giordano, Daniela, et al.
Publicado: (2017)

CD8 and CD4 T Cells in West Nile Virus Immunity and Pathogenesis
por: Netland, Jason, et al.
Publicado: (2013)

Rabies Virus Infection Induces Type I Interferon Production in an IPS-1 Dependent Manner While Dendritic Cell Activation Relies on IFNAR Signaling
por: Faul, Elizabeth J., et al.
Publicado: (2010)

Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA
por: Geiss, Brian J, et al.
Publicado: (2005)

Protective immune responses against West Nile virus are primed by distinct complement activation pathways
por: Mehlhop, Erin, et al.
Publicado: (2006)

Mechanisms of innate immune evasion in re-emerging RNA viruses
por: Ma, Daphne Y, et al.
Publicado: (2015)

Structural basis of West Nile virus neutralization by a therapeutic antibody
por: Nybakken, Grant E., et al.
Publicado: (2005)

West Nile virus infection in the golden hamster (Mesocricetus auratus): a model for West Nile encephalitis.
por: Xiao, S Y, et al.
Publicado: (2001)

STING is required for host defense against neuropathological West Nile virus infection
por: McGuckin Wuertz, Kathryn, et al.
Publicado: (2019)

Recent progress in West Nile virus diagnosis and vaccination
por: De Filette, Marina, et al.
Publicado: (2012)

Management of West Nile Encephalitis: An Uncommon Complication of West Nile Virus
por: Alli, Ammar, et al.
Publicado: (2021)

A Critical Role for Induced IgM in the Protection against West Nile Virus Infection
por: Diamond, Michael S., et al.
Publicado: (2003)

West Nile Virus in Farmed Alligators
por: Miller, Debra L., et al.
Publicado: (2003)

In vitro and in vivo characterization of a West Nile virus MAD78 infectious clone
por: Hussmann, Katherine L., et al.
Publicado: (2014)

Alligators as West Nile Virus Amplifiers
por: Klenk, Kaci, et al.
Publicado: (2004)

Evaluation of West Nile Virus Education Campaign
por: Averett, Ellen, et al.
Publicado: (2005)

Maturation of West Nile Virus Modulates Sensitivity to Antibody-Mediated Neutralization
por: Nelson, Steevenson, et al.
Publicado: (2008)

Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross
por: Green, Richard, et al.
Publicado: (2017)

RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection
por: Stone, Amy E. L., et al.
Publicado: (2019)

Generation and Analysis of Novel Plant-Derived Antibody-Based Therapeutic Molecules against West Nile Virus
por: He, Junyun, et al.
Publicado: (2014)

2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo
por: Szretter, Kristy J., et al.
Publicado: (2012)

Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis
por: Youn, Soonjeon, et al.
Publicado: (2013)

Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection
por: Wessel, Alex W., et al.
Publicado: (2021)

Protective Behavior and West Nile Virus Risk
por: Loeb, Mark, et al.
Publicado: (2005)

Correlation of West Nile Virus Incidence in Donated Blood with West Nile Neuroinvasive Disease Rates, United States, 2010–2012
por: Betsem, Edouard, et al.
Publicado: (2017)

A Therapeutic Antibody against West Nile Virus Neutralizes Infection by Blocking Fusion within Endosomes
por: Thompson, Bruce S., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_st6nn6le0qggaar2jsij9fsb2v