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Transient Dimers of Allergens
BACKGROUND: Allergen-mediated cross-linking of IgE antibodies bound to the FcεRI receptors on the mast cell surface is the key feature of the type I allergy. If an allergen is a homodimer, its allergenicity is enhanced because it would only need one type of antibody, instead of two, for cross-linkin...
Autores principales: | Rouvinen, Juha, Jänis, Janne, Laukkanen, Marja-Leena, Jylhä, Sirpa, Niemi, Merja, Päivinen, Tero, Mäkinen-Kiljunen, Soili, Haahtela, Tari, Söderlund, Hans, Takkinen, Kristiina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816702/ https://www.ncbi.nlm.nih.gov/pubmed/20140203 http://dx.doi.org/10.1371/journal.pone.0009037 |
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