Cargando…
Widespread Scleredema Accompanied with a Monoclonal Gammopathy in a Patient with Advanced Ankylosing Spondylitis
Scleredema is a rare cutaneous mucinosis characterized by chronic diffuse induration of the skin, and it is occasionally associated with a monoclonal gammopathy (MG). Ankylosing spondylitis (AS) is noted to be another, chronic systemic inflammatory disorder of the axial skeleton that may accompany t...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816857/ https://www.ncbi.nlm.nih.gov/pubmed/15201522 http://dx.doi.org/10.3346/jkms.2004.19.3.481 |
_version_ | 1782177146714718208 |
---|---|
author | Chang, Hyun Kyu Kim, You Chan Kwon, Bum Sun |
author_facet | Chang, Hyun Kyu Kim, You Chan Kwon, Bum Sun |
author_sort | Chang, Hyun Kyu |
collection | PubMed |
description | Scleredema is a rare cutaneous mucinosis characterized by chronic diffuse induration of the skin, and it is occasionally associated with a monoclonal gammopathy (MG). Ankylosing spondylitis (AS) is noted to be another, chronic systemic inflammatory disorder of the axial skeleton that may accompany the MG. However, patients with scleredema and AS accompanied with a MG have not been reported in the literature. We here report a 40-yr-old man with scleredema and advanced AS accompanied with a MG of IgA-kappa protein. Widespread, long-standing scleredema has been developed over 10 yrs after the initial manifestation of AS. It is uncertain whether the coexistence of scleredema and AS is more than coincidental. |
format | Text |
id | pubmed-2816857 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-28168572010-02-12 Widespread Scleredema Accompanied with a Monoclonal Gammopathy in a Patient with Advanced Ankylosing Spondylitis Chang, Hyun Kyu Kim, You Chan Kwon, Bum Sun J Korean Med Sci Case Report Scleredema is a rare cutaneous mucinosis characterized by chronic diffuse induration of the skin, and it is occasionally associated with a monoclonal gammopathy (MG). Ankylosing spondylitis (AS) is noted to be another, chronic systemic inflammatory disorder of the axial skeleton that may accompany the MG. However, patients with scleredema and AS accompanied with a MG have not been reported in the literature. We here report a 40-yr-old man with scleredema and advanced AS accompanied with a MG of IgA-kappa protein. Widespread, long-standing scleredema has been developed over 10 yrs after the initial manifestation of AS. It is uncertain whether the coexistence of scleredema and AS is more than coincidental. The Korean Academy of Medical Sciences 2004-06 2004-06-30 /pmc/articles/PMC2816857/ /pubmed/15201522 http://dx.doi.org/10.3346/jkms.2004.19.3.481 Text en Copyright © 2004 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Chang, Hyun Kyu Kim, You Chan Kwon, Bum Sun Widespread Scleredema Accompanied with a Monoclonal Gammopathy in a Patient with Advanced Ankylosing Spondylitis |
title | Widespread Scleredema Accompanied with a Monoclonal Gammopathy in a Patient with Advanced Ankylosing Spondylitis |
title_full | Widespread Scleredema Accompanied with a Monoclonal Gammopathy in a Patient with Advanced Ankylosing Spondylitis |
title_fullStr | Widespread Scleredema Accompanied with a Monoclonal Gammopathy in a Patient with Advanced Ankylosing Spondylitis |
title_full_unstemmed | Widespread Scleredema Accompanied with a Monoclonal Gammopathy in a Patient with Advanced Ankylosing Spondylitis |
title_short | Widespread Scleredema Accompanied with a Monoclonal Gammopathy in a Patient with Advanced Ankylosing Spondylitis |
title_sort | widespread scleredema accompanied with a monoclonal gammopathy in a patient with advanced ankylosing spondylitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816857/ https://www.ncbi.nlm.nih.gov/pubmed/15201522 http://dx.doi.org/10.3346/jkms.2004.19.3.481 |
work_keys_str_mv | AT changhyunkyu widespreadscleredemaaccompaniedwithamonoclonalgammopathyinapatientwithadvancedankylosingspondylitis AT kimyouchan widespreadscleredemaaccompaniedwithamonoclonalgammopathyinapatientwithadvancedankylosingspondylitis AT kwonbumsun widespreadscleredemaaccompaniedwithamonoclonalgammopathyinapatientwithadvancedankylosingspondylitis |