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Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studies
G-CSF is widely employed for the treatment of chemotherapy-induced neutropenia. Recently, neuroprotective effects of G-CSF in animal stroke models were discovered including infarct size reduction and enhancement of functional recovery. The underlying mechanisms of action of G-CSF in ischemia appear...
Autores principales: | Minnerup, Jens, Sevimli, Sevgi, Schäbitz, Wolf-Rüdiger |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816868/ https://www.ncbi.nlm.nih.gov/pubmed/20142989 http://dx.doi.org/10.1186/2040-7378-1-2 |
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