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Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studies

G-CSF is widely employed for the treatment of chemotherapy-induced neutropenia. Recently, neuroprotective effects of G-CSF in animal stroke models were discovered including infarct size reduction and enhancement of functional recovery. The underlying mechanisms of action of G-CSF in ischemia appear...

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Detalles Bibliográficos
Autores principales: Minnerup, Jens, Sevimli, Sevgi, Schäbitz, Wolf-Rüdiger
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816868/
https://www.ncbi.nlm.nih.gov/pubmed/20142989
http://dx.doi.org/10.1186/2040-7378-1-2

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