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Effect of DA-8159, a Selective Phosphodiesterase Type 5 Inhibitor, on Electroretinogram and Retinal Histology in Rabbits

DA-8159, a selective inhibitor of phosphodiesterase type 5, was developed as a new drug for erectile dysfunction. The effect of DA-8159 on the electroretinogram (ERG) and the retinal histopathology were evaluated in rabbits. The ERG was performed prior to, and 1 and 5 hr after DA-8159 (5 to 30 mg/kg...

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Detalles Bibliográficos
Autores principales: Cho, Ho Kyun, Kang, Kyung Koo, Ahn, Gook Jun, Shim, Hyun Joo, Kim, Won Bae
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816895/
https://www.ncbi.nlm.nih.gov/pubmed/15308852
http://dx.doi.org/10.3346/jkms.2004.19.4.586