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Nonlinear Dynamics of Nonsynonymous (d(N)) and Synonymous (d(S)) Substitution Rates Affects Inference of Selection
Selection modulates gene sequence evolution in different ways by constraining potential changes of amino acid sequences (purifying selection) or by favoring new and adaptive genetic variants (positive selection). The number of nonsynonymous differences in a pair of protein-coding sequences can be us...
Autores principales: | Wolf, Jochen B. W., Künstner, Axel, Nam, Kiwoong, Jakobsson, Mattias, Ellegren, Hans |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817425/ https://www.ncbi.nlm.nih.gov/pubmed/20333200 http://dx.doi.org/10.1093/gbe/evp030 |
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