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Probiotic Pre-treatment Reduces Gliclazide Permeation (ex vivo) in Healthy Rats but Increases It in Diabetic Rats to the Level Seen in Untreated Healthy Rats

AIM: To investigate the influence of probiotic pre-treatment on the permeation of the antidiabetic drug gliclazide in healthy and diabetic rats. METHODS: Wistar rats (age 2–3 months, weight 350 ± 50 g) were randomly allocated into one of 4 groups (N = 16 each group): healthy control, healthy probiot...

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Detalles Bibliográficos
Autores principales:	Al-Salami, Hani, Butt, Grant, Tucker, Ian, Skrbic, Ranko, Golocorbin-Kon, Svetlana, Mikov, Momir
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Inc 2008
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817444/ https://www.ncbi.nlm.nih.gov/pubmed/20157366 http://dx.doi.org/10.1111/j.1753-5174.2008.00006.x

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