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Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K(+) solution: insights into the interconversion of human telomeric G-quadruplex structures
Human telomeric DNA G-quadruplex has been considered as an attractive target for cancer therapeutic intervention. The telomeric sequence shows intrinsic structure polymorphism. Here we report a novel intramolecular G-quadruplex structure formed by a variant human telomeric sequence in K(+) solution....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817458/ https://www.ncbi.nlm.nih.gov/pubmed/19946019 http://dx.doi.org/10.1093/nar/gkp1029 |