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N(7)-Methylguanine at position 46 (m(7)G46) in tRNA from Thermus thermophilus is required for cell viability at high temperatures through a tRNA modification network
N(7)-methylguanine at position 46 (m(7)G46) in tRNA is produced by tRNA (m(7)G46) methyltransferase (TrmB). To clarify the role of this modification, we made a trmB gene disruptant (ΔtrmB) of Thermus thermophilus, an extreme thermophilic eubacterium. The absence of TrmB activity in cell extract from...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817472/ https://www.ncbi.nlm.nih.gov/pubmed/19934251 http://dx.doi.org/10.1093/nar/gkp1059 |