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Collagen V-induced nasal tolerance downregulates pulmonary collagen mRNA gene and TGF-beta expression in experimental systemic sclerosis

BACKGROUND: The purpose of this study was to evaluate collagen deposition, mRNA collagen synthesis and TGF-beta expression in the lung tissue in an experimental model of scleroderma after collagen V-induced nasal tolerance. METHODS: Female New Zealand rabbits (N = 12) were immunized with 1 mg/ml of...

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Detalles Bibliográficos
Autores principales:	Velosa, Ana Paula P, Teodoro, Walcy R, dos Anjos, Daniel M, Konno, Renata, Oliveira, Cristiane C, Katayama, Maria LH, Parra, Edwin R, Capelozzi, Vera L, Yoshinari, Natalino H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817654/ https://www.ncbi.nlm.nih.gov/pubmed/20047687 http://dx.doi.org/10.1186/1465-9921-11-1

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