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Functional Overlap between eIF4G Isoforms in Saccharomyces cerevisiae

Initiation factor eIF4G is a key regulator of eukaryotic protein synthesis, recognizing proteins bound at both ends of an mRNA to help recruit messages to the small (40S) ribosomal subunit. Notably, the genomes of a wide variety of eukaryotes encode multiple distinct variants of eIF4G. We found that...

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Detalles Bibliográficos
Autores principales: Clarkson, Bryan K., Gilbert, Wendy V., Doudna, Jennifer A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817733/
https://www.ncbi.nlm.nih.gov/pubmed/20161741
http://dx.doi.org/10.1371/journal.pone.0009114