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Functional Overlap between eIF4G Isoforms in Saccharomyces cerevisiae
Initiation factor eIF4G is a key regulator of eukaryotic protein synthesis, recognizing proteins bound at both ends of an mRNA to help recruit messages to the small (40S) ribosomal subunit. Notably, the genomes of a wide variety of eukaryotes encode multiple distinct variants of eIF4G. We found that...
Autores principales: | Clarkson, Bryan K., Gilbert, Wendy V., Doudna, Jennifer A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817733/ https://www.ncbi.nlm.nih.gov/pubmed/20161741 http://dx.doi.org/10.1371/journal.pone.0009114 |
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