ENU Mutagenesis Reveals a Novel Phenotype of Reduced Limb Strength in Mice Lacking Fibrillin 2

BACKGROUND: Fibrillins 1 (FBN1) and 2 (FBN2) are components of microfibrils, microfilaments that are present in many connective tissues, either alone or in association with elastin. Marfan's syndrome and congenital contractural arachnodactyly (CCA) result from dominant mutations in the genes FB...

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Detalles Bibliográficos
Autores principales: Miller, Gaynor, Neilan, Monica, Chia, Ruth, Gheryani, Nabeia, Holt, Natalie, Charbit, Annabelle, Wells, Sara, Tucci, Valter, Lalanne, Zuzanne, Denny, Paul, Fisher, Elizabeth M. C., Cheeseman, Michael, Askew, Graham N., Dear, T. Neil
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817753/
https://www.ncbi.nlm.nih.gov/pubmed/20161761
http://dx.doi.org/10.1371/journal.pone.0009137

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