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Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study

Objective To characterise whether some selective serotonin reuptake inhibitor (SSRI) antidepressants reduce tamoxifen’s effectiveness by inhibiting its bioactivation by cytochrome P450 2D6 (CYP2D6). Design Population based cohort study. Participants Women living in Ontario aged 66 years or older tre...

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Detalles Bibliográficos
Autores principales: Kelly, Catherine M, Juurlink, David N, Gomes, Tara, Duong-Hua, Minh, Pritchard, Kathleen I, Austin, Peter C, Paszat, Lawrence F
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817754/
https://www.ncbi.nlm.nih.gov/pubmed/20142325
http://dx.doi.org/10.1136/bmj.c693