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Diabetic Retinopathy and Peripapillary Retinal Thickness

PURPOSE: To assess the diagnostic efficacy of macular and peripapillary retinal thickness measurements for the staging of diabetic retinopathy (DR) and the prediction of disease progression. METHODS: In this prospective study, 149 diabetic patients (149 eyes) and 50 non-diabetic control subjects wer...

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Autores principales: Cho, Hee Yoon, Lee, Dong Hoon, Chung, Song Ee, Kang, Se Woong
Formato: Texto
Lenguaje:English
Publicado: The Korean Ophthalmological Society 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817818/
https://www.ncbi.nlm.nih.gov/pubmed/20157409
http://dx.doi.org/10.3341/kjo.2010.24.1.16
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author Cho, Hee Yoon
Lee, Dong Hoon
Chung, Song Ee
Kang, Se Woong
author_facet Cho, Hee Yoon
Lee, Dong Hoon
Chung, Song Ee
Kang, Se Woong
author_sort Cho, Hee Yoon
collection PubMed
description PURPOSE: To assess the diagnostic efficacy of macular and peripapillary retinal thickness measurements for the staging of diabetic retinopathy (DR) and the prediction of disease progression. METHODS: In this prospective study, 149 diabetic patients (149 eyes) and 50 non-diabetic control subjects were included. Baseline optical coherence tomography was employed to measure retinal thickness in the macula (horizontal, vertical, and central) and the peripapillary zone (superior, inferior, nasal, and concentric to the optic disc). Seven baseline parameters were correlated with the DR stages identified by fluorescein angiography. Baseline retinal thickness was compared between groups of patients requiring panretinal photocoagulation (PRP) within 6 months (PRP group) and patients not requiring PRP (No-PRP group). RESULTS: Macular and peripapillary retinal thicknesses in diabetic subjects were significantly greater than that in normal controls (p<0.05). All retinal thickness parameters, and particularly peripapillary circular scans, tended to increase with increasing DR severity (p<0.05). The baseline thicknesses of the peripapillary circular scans were greater in the PRP group than in the no-PRP group (p<0.05). CONCLUSIONS: Peripapillary retinal thickness may prove to be a useful criterion for DR severity and may also serve as an indicator of disease progression.
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spelling pubmed-28178182010-02-12 Diabetic Retinopathy and Peripapillary Retinal Thickness Cho, Hee Yoon Lee, Dong Hoon Chung, Song Ee Kang, Se Woong Korean J Ophthalmol Original Article PURPOSE: To assess the diagnostic efficacy of macular and peripapillary retinal thickness measurements for the staging of diabetic retinopathy (DR) and the prediction of disease progression. METHODS: In this prospective study, 149 diabetic patients (149 eyes) and 50 non-diabetic control subjects were included. Baseline optical coherence tomography was employed to measure retinal thickness in the macula (horizontal, vertical, and central) and the peripapillary zone (superior, inferior, nasal, and concentric to the optic disc). Seven baseline parameters were correlated with the DR stages identified by fluorescein angiography. Baseline retinal thickness was compared between groups of patients requiring panretinal photocoagulation (PRP) within 6 months (PRP group) and patients not requiring PRP (No-PRP group). RESULTS: Macular and peripapillary retinal thicknesses in diabetic subjects were significantly greater than that in normal controls (p<0.05). All retinal thickness parameters, and particularly peripapillary circular scans, tended to increase with increasing DR severity (p<0.05). The baseline thicknesses of the peripapillary circular scans were greater in the PRP group than in the no-PRP group (p<0.05). CONCLUSIONS: Peripapillary retinal thickness may prove to be a useful criterion for DR severity and may also serve as an indicator of disease progression. The Korean Ophthalmological Society 2010-02 2010-02-05 /pmc/articles/PMC2817818/ /pubmed/20157409 http://dx.doi.org/10.3341/kjo.2010.24.1.16 Text en © 2010 The Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Cho, Hee Yoon
Lee, Dong Hoon
Chung, Song Ee
Kang, Se Woong
Diabetic Retinopathy and Peripapillary Retinal Thickness
title Diabetic Retinopathy and Peripapillary Retinal Thickness
title_full Diabetic Retinopathy and Peripapillary Retinal Thickness
title_fullStr Diabetic Retinopathy and Peripapillary Retinal Thickness
title_full_unstemmed Diabetic Retinopathy and Peripapillary Retinal Thickness
title_short Diabetic Retinopathy and Peripapillary Retinal Thickness
title_sort diabetic retinopathy and peripapillary retinal thickness
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817818/
https://www.ncbi.nlm.nih.gov/pubmed/20157409
http://dx.doi.org/10.3341/kjo.2010.24.1.16
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