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Diabetic Retinopathy and Peripapillary Retinal Thickness
PURPOSE: To assess the diagnostic efficacy of macular and peripapillary retinal thickness measurements for the staging of diabetic retinopathy (DR) and the prediction of disease progression. METHODS: In this prospective study, 149 diabetic patients (149 eyes) and 50 non-diabetic control subjects wer...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Ophthalmological Society
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817818/ https://www.ncbi.nlm.nih.gov/pubmed/20157409 http://dx.doi.org/10.3341/kjo.2010.24.1.16 |
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author | Cho, Hee Yoon Lee, Dong Hoon Chung, Song Ee Kang, Se Woong |
author_facet | Cho, Hee Yoon Lee, Dong Hoon Chung, Song Ee Kang, Se Woong |
author_sort | Cho, Hee Yoon |
collection | PubMed |
description | PURPOSE: To assess the diagnostic efficacy of macular and peripapillary retinal thickness measurements for the staging of diabetic retinopathy (DR) and the prediction of disease progression. METHODS: In this prospective study, 149 diabetic patients (149 eyes) and 50 non-diabetic control subjects were included. Baseline optical coherence tomography was employed to measure retinal thickness in the macula (horizontal, vertical, and central) and the peripapillary zone (superior, inferior, nasal, and concentric to the optic disc). Seven baseline parameters were correlated with the DR stages identified by fluorescein angiography. Baseline retinal thickness was compared between groups of patients requiring panretinal photocoagulation (PRP) within 6 months (PRP group) and patients not requiring PRP (No-PRP group). RESULTS: Macular and peripapillary retinal thicknesses in diabetic subjects were significantly greater than that in normal controls (p<0.05). All retinal thickness parameters, and particularly peripapillary circular scans, tended to increase with increasing DR severity (p<0.05). The baseline thicknesses of the peripapillary circular scans were greater in the PRP group than in the no-PRP group (p<0.05). CONCLUSIONS: Peripapillary retinal thickness may prove to be a useful criterion for DR severity and may also serve as an indicator of disease progression. |
format | Text |
id | pubmed-2817818 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | The Korean Ophthalmological Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-28178182010-02-12 Diabetic Retinopathy and Peripapillary Retinal Thickness Cho, Hee Yoon Lee, Dong Hoon Chung, Song Ee Kang, Se Woong Korean J Ophthalmol Original Article PURPOSE: To assess the diagnostic efficacy of macular and peripapillary retinal thickness measurements for the staging of diabetic retinopathy (DR) and the prediction of disease progression. METHODS: In this prospective study, 149 diabetic patients (149 eyes) and 50 non-diabetic control subjects were included. Baseline optical coherence tomography was employed to measure retinal thickness in the macula (horizontal, vertical, and central) and the peripapillary zone (superior, inferior, nasal, and concentric to the optic disc). Seven baseline parameters were correlated with the DR stages identified by fluorescein angiography. Baseline retinal thickness was compared between groups of patients requiring panretinal photocoagulation (PRP) within 6 months (PRP group) and patients not requiring PRP (No-PRP group). RESULTS: Macular and peripapillary retinal thicknesses in diabetic subjects were significantly greater than that in normal controls (p<0.05). All retinal thickness parameters, and particularly peripapillary circular scans, tended to increase with increasing DR severity (p<0.05). The baseline thicknesses of the peripapillary circular scans were greater in the PRP group than in the no-PRP group (p<0.05). CONCLUSIONS: Peripapillary retinal thickness may prove to be a useful criterion for DR severity and may also serve as an indicator of disease progression. The Korean Ophthalmological Society 2010-02 2010-02-05 /pmc/articles/PMC2817818/ /pubmed/20157409 http://dx.doi.org/10.3341/kjo.2010.24.1.16 Text en © 2010 The Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Cho, Hee Yoon Lee, Dong Hoon Chung, Song Ee Kang, Se Woong Diabetic Retinopathy and Peripapillary Retinal Thickness |
title | Diabetic Retinopathy and Peripapillary Retinal Thickness |
title_full | Diabetic Retinopathy and Peripapillary Retinal Thickness |
title_fullStr | Diabetic Retinopathy and Peripapillary Retinal Thickness |
title_full_unstemmed | Diabetic Retinopathy and Peripapillary Retinal Thickness |
title_short | Diabetic Retinopathy and Peripapillary Retinal Thickness |
title_sort | diabetic retinopathy and peripapillary retinal thickness |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817818/ https://www.ncbi.nlm.nih.gov/pubmed/20157409 http://dx.doi.org/10.3341/kjo.2010.24.1.16 |
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